I thought it might be when I installed the AMD driver, but I tried uninstalling it and it didn't help. I'm not sure if the brightness settings ever worked after the Windows 10 reinstall, and if they did, I do not know at what point they stopped working. There are no brightness settings in the control panel power settings, and when I click the battery icon on the taskbar (Windows 10), the brightness option is grayed out! The Windows Mobility Centre brightness control allows me to move the slider but there is no actual change in brightness. Not only do they not work with the keyboard, I also cannot adjust the brightness any other way. Save Big on Toshiba Windows 10 PC Laptops & Netbooks and our wide variety of models like Toshiba Satellite Pro, Samsung ChromeBook, Samsung Chromebook 2 & more. After installing the Function Key Desktop App every single one of the Fn keys worked without pressing the Fn button, apart from Brightness Up and Brightness Down, which didn't work at all with or without the Fn key. Straight after the Windows 10 reinstall, the Fn keys (volume, flight mode etc) worked when I held down the Fn key, which wasn't what I wanted. I have since reinstalled the AMD graphics driver, the Toshiba Function Key Desktop App, The Toshiba Value Added Package (this only gave me the battery manger and the PC diagnostic tool), so I then manually found and installed the Toshiba System Settings and the Toshiba HWsetup Utility. I recently reinstalled Windows 10, and so lost all of the Toshiba software that came with the laptop.